Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1
نویسندگان
چکیده
منابع مشابه
Redox modulation of NQO1
NQO1 is a FAD containing NAD(P)H-dependent oxidoreductase that catalyzes the reduction of quinones and related substrates. In cells, NQO1 participates in a number of binding interactions with other proteins and mRNA and these interactions may be influenced by the concentrations of reduced pyridine nucleotides. NAD(P)H can protect NQO1 from proteolytic digestion suggesting that binding of reduce...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2009
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2009.04.016